The toxicity of Cassia senna to Nubian goats

Ten Nubian goats were given oral doses of the fresh fruits and leaves of Cassia senna at 1, 5, and 10 g/kg/day. Eight goats died within 30 days and two others were slaughtered in a moribund condition on days 18 and 29. The clinical signs of diarrhoea, inappetence, loss of condition, and dyspnea were well correlated with the pathological findings. There was an increase in G.O.T., ammonia, urea, and total cholesterol and a decrease in total protein in the serum of Cassia-poisoned goats. Blood sugar level was reduced and the increase in the values of Hb, PCV, and RBC was due to haemoconcentration.