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The SCMC test: a screening test for spermatozoal antibodies
Andrologia
|May 1, 1983
Summary
The sperm cervical mucus contact test (SCMC-test) effectively identifies sperm antibodies in infertile couples. This reliable screening method aids in diagnosing unexplained infertility cases with poor post-coital test results.
Area of Science:
- Reproductive immunology
- Infertility diagnostics
Background:
- Sperm antibodies can impair fertility.
- Post-coital tests assess sperm-mucus interaction but can be inconclusive.
Purpose of the Study:
- To evaluate the diagnostic reliability of the sperm cervical mucus contact test (SCMC-test).
- To assess the SCMC-test's utility in detecting sperm antibodies in infertile couples with poor post-coital test results.
Main Methods:
- The sperm cervical mucus contact test (SCMC-test) was performed on 62 couples.
- Results were compared with tray-agglutination and mixed antiglobulin reaction tests in some cases.
Main Results:
- 15 out of 17 couples (88%) with consistently poor post-coital tests showed a positive SCMC-test.
- SCMC-test results were corroborated by other immunological tests in 10 instances.
Conclusions:
- The SCMC-test is a dependable screening tool for detecting sperm antibodies.
- This test is valuable for investigating infertility in couples with unexplained poor post-coital test findings.