Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A recursive algorithm for inferring gene origins.

E A Thompson

    Annals of Human Genetics
    |May 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces advanced algorithms for analyzing gene origins in family trees. These methods enable more comprehensive genetic analyses than previously possible.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Evidence for the Collective Nature of Radial Flow in Pb+Pb Collisions with the ATLAS Detector.

    Physical review letters·2026
    Same author

    Evidence for the Dimuon Decay of the Higgs Boson in pp Collisions with the ATLAS Detector.

    Physical review letters·2025
    Same author

    Evidence for Longitudinally Polarized W Bosons in the Electroweak Production of Same-Sign W Boson Pairs in Association with Two Jets in pp Collisions at sqrt[s]=13  TeV with the ATLAS Detector.

    Physical review letters·2025
    Same author

    Observation of tt[over ¯] Production in Pb+Pb Collisions at sqrt[s_{NN}]=5.02  TeV with the ATLAS Detector.

    Physical review letters·2025
    Same author

    Search for Dark Matter Produced in Association with a Dark Higgs Boson in the bb[over ¯] Final State Using pp Collisions at sqrt[s]=13  TeV with the ATLAS Detector.

    Physical review letters·2025
    Same author

    Spatially defined intratumoral immune biomarkers predict recurrent versus second primary tumors in non-small cell lung cancer.

    Precision clinical medicine·2025
    Same journal

    FIGLA Novel Variant c.385-9G>A Affects RNA Splicing in a Minigene Assay.

    Annals of human genetics·2026
    Same journal

    Epigenetic Shifts in MTNR1A, MTNR1B and Fn14 and Their Links to Preeclampsia Risk.

    Annals of human genetics·2026
    Same journal

    Hip Bone Marrow Adiposity as a Risk Factor for Alzheimer's Disease: Insights From Mendelian Randomization Analysis.

    Annals of human genetics·2026
    Same journal

    A Novel Biallelic REL Frameshift Variant p.(Tyr9Ilefs*2) Causing Immunodeficiency-92 With Profound c-Rel Deficiency.

    Annals of human genetics·2026
    Same journal

    Identification of PSMA4 as a Therapeutic Target for Atherosclerosis: A Comprehensive Multiomics Mendelian Randomization Analysis.

    Annals of human genetics·2026
    Same journal

    Genetic Insights Into Hypertension and Breast Cancer Risk in African Women: A Mendelian Randomization and Colocalization Analyses.

    Annals of human genetics·2026
    See all related articles

    Area of Science:

    • Genetics
    • Computational Biology
    • Statistical Genetics

    Background:

    • Previous studies on allelic origins in complex genealogies were limited by computational constraints.
    • Dependencies between ancestors and sibships were not fully considered in earlier analyses.

    Purpose of the Study:

    • To extend the analysis of allelic origins in complex genealogies.
    • To adapt recursive algorithms for computing joint descent probabilities of multiple genes.

    Main Methods:

    • Development of algorithms similar to Karigl's (1981) for multiple kinship coefficients.
    • Application of these algorithms to calculate probabilities of joint gene descent from ancestral genes.

    Main Results:

    • Demonstrated the applicability of recursive algorithms to gene descent probabilities.

    Related Experiment Videos

  • Enabled a more extensive analysis of allelic origins in large genealogies.

    • Conclusions:

    • The new algorithms significantly enhance the scope and depth of genetic analyses in complex family structures.
    • Facilitates a more thorough investigation into the inheritance patterns of genetic traits.