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[Intracranial hypertension].

H Mogami, Y Ushio, T Hayakawa

    Gan to Kagaku Ryoho. Cancer & Chemotherapy
    |February 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Intracranial hypertension, often caused by brain tumors, requires prompt management. Treatments focus on reducing pressure via medications, cerebrospinal fluid drainage, or tumor removal to improve patient outcomes.

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    Area of Science:

    • Neurology
    • Oncology
    • Neurosurgery

    Context:

    • Intracranial hypertension (IH) presents diverse oncologic etiologies, including space-occupying lesions, leptomeningeal tumors, and tumor-related hemorrhage or thrombosis.
    • Brain edema and cerebrospinal fluid (CSF) circulation disturbances are key contributors to increased intracranial pressure (ICP) in brain tumor patients, often more significant than tumor volume.

    Purpose:

    • To outline the oncologic causes of intracranial hypertension.
    • To describe diagnostic utility of CT scans.
    • To review immediate and long-term therapeutic strategies for managing elevated ICP in the context of brain tumors.

    Summary:

    • Oncologic intracranial hypertension stems from various tumor-related processes. Management involves prompt interventions like hyperventilation, osmotherapy (mannitol, glycerol), steroids for edema, CSF drainage/shunting, and definitive tumor treatment (resection, radiotherapy, chemotherapy).

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  • CT scans are crucial for diagnosing the underlying cause of IH.
  • Therapeutic approaches are tailored to the specific cause and severity of ICP elevation, aiming to reduce pressure and address the primary oncologic issue.

    • Impact:

    • Provides a comprehensive overview of oncologic causes and management of intracranial hypertension.
    • Highlights the importance of prompt diagnosis and multimodal treatment strategies.
    • Informs clinical decision-making for neuro-oncology patients experiencing elevated intracranial pressure.