[Effect of ischemia and postischemic circulatory recovery on the ultrastructure of neurons]

In the investigation performed, a comparative analysis on the effect of ischemia and postischemic recirculation upon the neuron in the rat cerebral cortex and the dog spinal ganglia, common regularities and differences in appearance of pathological ultrastructural alterations were revealed. A general tendency towards increasing gravity of the pathological alterations was noted, as the period of ischemia and recirculation grew large. A leading type of the changes in the group of the injured neurons both in the spinal ganglia and in the cerebral cortex were changes of a chromatolitic type and they made one more general regularity. Hyperchromatosis was presented by an essentially less number of cases. The differences observed were presented as a rather greater polymorphism in the cortical neurons alterations comparing to the spinal ganglia cells at ischemia and postischemic recirculation. Besides, in the cortical neurons, more sensitive to the ischemic factor, diverced forms of the compensatory-adaptive reactions were revealed, that demonstrated plastic potentials of the cortical neurons.