Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Butterfly-shaped macular dystrophy in four generations.

J G Prensky, G H Bresnick

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |August 1, 1983
    PubMed
    Summary

    This study details a rare butterfly-shaped macular dystrophy affecting four generations. Progressive vision loss and fundus changes highlight diagnostic challenges in advanced cases of this inherited eye condition.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A screening approach to the surveillance of patients with diabetes for the presence of vision-threatening retinopathy.

    Ophthalmology·2000
    Same author

    Protein C and protein S deficiency associated with retinal, optic nerve, and cerebral ischaemia.

    The British journal of ophthalmology·2000
    Same author

    Impaired color vision associated with diabetic retinopathy: Early Treatment Diabetic Retinopathy Study Report No. 15.

    American journal of ophthalmology·1999
    Same author

    Barriers to compliance with screening guidelines for diabetic retinopathy.

    Ophthalmic epidemiology·1999
    Same author

    Brachydactyly-short stature-hypertension (Bilginturan) syndrome: report on two families.

    American journal of medical genetics·1998
    Same author

    Resuturing the scleral flap leads to resolution of hypotony maculopathy.

    Journal of glaucoma·1996

    Area of Science:

    • Ophthalmology
    • Medical Genetics

    Background:

    • Butterfly-shaped macular dystrophy is an inherited retinal disorder.
    • Autosomal dominant inheritance patterns are characteristic.

    Observation:

    • Four generations of a family exhibited the condition, with affected individuals aged 8 to 77.
    • Key features included bilateral, symmetrical pigmented macular lesions and reduced electrooculographic light peak-dark trough ratio.

    Findings:

    • Progressive chorioretinal atrophy around the optic disc and macula was observed.
    • Enlarged blind spots and paracentral scotomas leading to diminished visual acuity were noted in later stages.
    • The evolving fundus appearance can complicate diagnosis in advanced stages.

    Implications:

    • Understanding the progressive nature of this dystrophy is crucial for timely diagnosis.
    • Recognizing late-stage changes can prevent misdiagnosis of butterfly-shaped macular dystrophy.
    • Further research into the genetic and clinical progression is warranted.

    Related Experiment Videos