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Updated: Aug 18, 2026
08:56
Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
Published on: February 10, 2015
[Effect of indoprofen on biliary secretion in the rat]
Abstract:
The activity of indoprophen on biliary secretion of rats has been investigated. Indoprophen, at a dose of 20 mg/kg induces a marked choleretic effect. It has been hypothesized that the choleretic action of indoprophen could be attributed to an inhibition of prostaglandin-synthetase and to an increase of cAMP which is the physiological factor responsible of ductal choleresis.
