[Pathway of synthesis of the aldehyde factor - a basic substrate of luciferase]

The stimulation of luminescence and cell aldehyde factor during the growth of one-aldehyde-dependent mutant in the condition medium by other aldehyde-dependent mutants was studied. It was shown that the aldehyde factor is synthesized in five successive steps, thus suggesting the participation of five enzymes in aldehyde factor synthesis. The metabolite accumulation in the condition medium increases both the level of the aldehyde factor and that of luciferase. It is assumed that some precursors of the aldehyde factor are involved in the regulation of the luminescence development.