Related Experiment Video
Updated: Jul 31, 2026
11:26
Analyzing Oxygen Consumption Rate in Primary Cultured Mouse Neonatal Cardiomyocytes Using an Extracellular Flux Analyzer
Published on: February 13, 2019
Capacity of cyclic urea synthesis in neonatal rat liver
Biology of the Neonate
|January 1, 1983
Abstract:
The optimal conditions for the measurements of the capacity of cyclic urea formation was determined using tissue homogenate. Under these conditions, the capacity of cyclic urea synthesis in adult rat liver was 1.10 mumol/min/g wet tissue. On the other hand, the capacity of fetal liver was very low. After parturition, the capacity increased rapidly in 24 h to one-quarter of the adult level, and by weaning age it reached one-half the adult level.
Related Concept Videos
01:23Urea Cycle
The urea cycle describes how liver cells convert ammonia to urea. Ammonia is a toxic waste product of protein catabolism. Land animals must convert ammonia into the less toxic urea which can be safely eliminated by the kidneys through urine. Marine animals excrete ammonia directly, and the surrounding water dilutes the ammonia to safe levels.
01:28Biosynthesis of Nucleic Acids
Nucleic acid biosynthesis is a fundamental biochemical process that produces the purine and pyrimidine nucleotides essential for DNA and RNA synthesis. This pathway maintains a balanced nucleotide pool, preventing imbalances that could jeopardize genetic integrity and cellular function. Given the crucial role of nucleotides, their synthesis is tightly regulated to ensure proper cellular homeostasis.Purine BiosynthesisThe biosynthesis of purine nucleotides begins with ribose-5-phosphate, a...