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Applicability of a scoring system in the diagnosis of streptococcal pharyngitis
Clinical Pediatrics
|September 1, 1983
Abstract:
The usefulness of a scoring system, developed in a private pediatric practice, for the early diagnosis of streptococcal pharyngitis has been evaluated in a teaching hospital. The system, evaluated in 892 patients, appears most useful in predicting culture-negative patients (80%). A false positive rate of 20 per cent precludes the use of the scoring system in the decision to initiate antibiotic therapy at our institution.
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Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
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Classification
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Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...

