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Mesodermal cyst of the spleen: computed tomographic characteristics and pathogenetic considerations
The Journal of Computed Tomography
|August 1, 1983
Summary
A benign splenic cyst in a young woman was diagnosed using imaging. Histology suggests it originates from primitive coelomic mesothelial cells, proposing "mesodermal cyst" as a more accurate term.
Area of Science:
- Surgical pathology
- Diagnostic imaging
- Embryology
Background:
- Benign splenic cysts are rare, and their exact origin can be unclear.
- Accurate diagnosis is crucial for appropriate patient management.
Observation:
- A large, nonparasitic, non-neoplastic, benign cyst was identified in a 24-year-old woman.
- Imaging modalities including radiography, radionuclide scintigraphy, and computed tomography (CT) were used for diagnosis.
Findings:
- Characteristic CT features included round contour, sharp margins, and homogeneous low-attenuation content.
- Histologic examination and literature review supported the hypothesis of origin from embryonal rests of primitive coelomic mesothelial cells.
- The term 'mesodermal cyst' is proposed as a more appropriate designation.
Implications:
- Understanding the embryological origin aids in classifying splenic cysts.
- This classification may refine diagnostic criteria and treatment strategies for splenic lesions.