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Rheological aspects of cerebrovascular disease
European Neurology
|January 1, 1983
Insights
Blood flow disturbances, or abnormal rheology, affect over 40% of cardiovascular disease (CVD) patients. These issues, marked by increased blood viscosity, stem from both cellular and plasma-related factors.
Area of Science:
- Cardiovascular Science
- Hematology
- Biophysics
Background:
- Cardiovascular disease (CVD) affects a significant portion of the population.
- Blood flow properties (rheology) are crucial for circulatory health.
- Disturbances in blood rheology are increasingly recognized as contributing factors in CVD.
Purpose of the Study:
- To highlight the prevalence of rheological disturbances in CVD patients.
- To explain the concept of abnormal rheology in CVD.
- To identify potential causes of altered blood flow properties.
Main Methods:
- Literature review on blood rheology in cardiovascular disease.
- Analysis of studies measuring blood viscosity.
- Categorization of factors influencing rheological abnormalities.
Main Results:
- Over 40% of patients with cardiovascular disease exhibit disturbances in blood flow properties.
- Abnormal rheology is quantifiable as increased blood viscosity.
- Causes of increased viscosity include both corpuscular (e.g., red blood cells, platelets) and plasmatic (e.g., fibrinogen, proteins) factors.
Conclusions:
- Rheological disturbances are common in cardiovascular disease.
- Increased blood viscosity is a key indicator of abnormal rheology.
- Both cellular and plasma components of blood contribute to these flow property alterations.
Abstract:
Disturbances of the flow properties of the blood may occur in more than 40% of patients with CVD. Abnormal rheologic conditions can be measured as increased blood viscosity and may be caused by corpuscular as well as by plasmatic factors.