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Hereditary progressive retinal atrophy in the Abyssinian cat
The Journal of Heredity
|July 1, 1983
Summary
Progressive retinal atrophy (PRA) affects Abyssinian cats, causing blindness due to an autosomal recessive gene. This hereditary eye disease was observed in 45% of cats over two years old in Sweden.
Area of Science:
- Veterinary Ophthalmology
- Genetics
- Animal Health
Background:
- Progressive retinal atrophy (PRA) is a hereditary eye disease causing blindness.
- Abyssinian cats are identified as a breed affected by PRA.
Purpose of the Study:
- To investigate the prevalence and characteristics of PRA in Abyssinian cats.
- To determine the genetic basis of PRA in this breed.
Main Methods:
- Ophthalmoscopic examinations of 68 cats over a 2-year period in Sweden.
- Genetic analysis to identify the mode of inheritance.
Main Results:
- Bilateral generalized retinopathy was observed in various stages.
- PRA was diagnosed as early as 16 months, with atrophy typically present by 3-4 years.
- Forty-five percent of Abyssinian cats aged 2 years and older were affected.
Conclusions:
- PRA is a significant hereditary eye disease in the Abyssinian cat breed.
- The condition is caused by an autosomal recessive gene.
- Early diagnosis and genetic understanding are crucial for management.
