Multiple recurrences of meningiomas

Area of Science:

• Neurosurgery
• Oncology
• Pathology

Background:

• Meningiomas are tumors arising from the meninges.
• Recurrence and multifocal development pose clinical challenges.
• Sphenoid wing and parasagittal locations are common sites.

Observation:

• A patient presented with a new right parasagittal frontoparietal meningioma.
• This diagnosis occurred 25 years post-resection of a right sphenoid wing meningioma.
• No signs of neurofibromatosis type 1 (Von Recklinghausen disease) were present.

Findings:

• Both the initial and subsequent meningiomas were histologically benign.
• The patient exhibited multifocal meningioma development over a long interval.
• Absence of genetic predisposition (e.g., Von Recklinghausen disease) noted.

Implications:

• This case underscores the potential for late recurrence or new primary meningiomas.
• It emphasizes the need for long-term surveillance in patients with a history of meningioma.
• Understanding mechanisms of multifocal meningioma development is crucial for improved patient management.