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Left ventricular function in chronic obstructive pulmonary disease.

R G Kachel

    Chest
    |September 1, 1978
    PubMed
    Summary

    Most patients with chronic obstructive pulmonary disease (COPD) have normal left ventricular function, despite clinical symptoms suggesting heart failure. Minor abnormalities may exist but are not clinically significant.

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    Area of Science:

    • Cardiology
    • Pulmonology
    • Internal Medicine

    Background:

    • Left ventricular dysfunction in chronic obstructive pulmonary disease (COPD) remains a topic of debate.
    • Clinical symptoms of left-sided failure can be unreliable in COPD patients.

    Purpose of the Study:

    • To review evidence on left ventricular (LV) function in COPD patients.
    • To determine the prevalence and clinical significance of LV dysfunction in COPD.

    Main Methods:

    • Review of pathological abnormalities.
    • Evaluation of methods for assessing LV performance.
    • Analysis of systolic time intervals, LV end-diastolic pressure, ejection fraction, isovolumic indices, and LV function curves.
    • Consideration of experimental data.

    Main Results:

    • The majority of COPD patients exhibit normal left ventricular function after excluding other causes.
    • A small subset of patients may show minor, clinically insignificant LV performance abnormalities.

    Conclusions:

    • Clinical assessment of heart failure in COPD is often unreliable.
    • Significant left ventricular dysfunction is uncommon in COPD patients.
    • Further research is needed to understand the long-term implications of minor LV abnormalities in COPD.

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