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[Myocardial contractility in newborns following tokolysis with beta-sympathicomimetics]
Using non-invasive methods (carotic pulse sphygmography, electro- and phonocardiography) the effect of maternal tokolysis with beta-sympathicomimetics (Fenoterol in combination with Verapamil) on the systolic intervals in neonates was investigated as a global measurement of cardiac capacity. In 39 newborns (gestational age 35.1 +/- 1.7 weeks), after an average duration of tokolysis of 37.5 days (1-210) with normal birth and normal primary adaptation, the findings as compared with a control group of 22 neonates were as follows: increased pre-ejection time (80.7 +/- 20 as compared with 67.5 +/- 7.5 ms), increased intraventricular time (38.6 +/- 14.3 as compared with 34.9 +/- 7.0 ms) and a higher quotient of pre-ejection and left-ventricular ejection time (0.476 +/- 0.127 as compared with 0.369 +/- 0.06). There are statistically established correlations with the duration of tokolysis. The findings suggest a myocardial is as a rule successfully compensated for by an increase in heart rate, and which disappears in the course of the first week of life.
Using non-invasive methods (carotic pulse sphygmography, electro- and phonocardiography) the effect of maternal tokolysis with beta-sympathicomimetics (Fenoterol in combination with Verapamil) on the systolic intervals in neonates was investigated as a global measurement of cardiac capacity. In 39 newborns (gestational age 35.1 +/- 1.7 weeks), after an average duration of tokolysis of 37.5 days (1-210) with normal birth and normal primary adaptation, the findings as compared with a control group of 22 neonates were as follows: increased pre-ejection time (80.7 +/- 20 as compared with 67.5 +/- 7.5 ms), increased intraventricular time (38.6 +/- 14.3 as compared with 34.9 +/- 7.0 ms) and a higher quotient of pre-ejection and left-ventricular ejection time (0.476 +/- 0.127 as compared with 0.369 +/- 0.06). There are statistically established correlations with the duration of tokolysis. The findings suggest a myocardial is as a rule successfully compensated for by an increase in heart rate, and which disappears in the course of the first week of life.