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Vitrectomy in uveitis associated with ankylosing spondylitis.

J B Belmont, J B Michelson

    American Journal of Ophthalmology
    |September 1, 1982
    PubMed
    Summary
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    Ophthalmology·1990

    Ankylosing spondylitis patients with chronic iridocyclitis experienced vitreous opacification. Vitrectomy improved vision by clearing the vitreous, though macular edema remained a limitation.

    Area of Science:

    • Ophthalmology
    • Rheumatology
    • Immunology

    Background:

    • Ankylosing spondylitis is an inflammatory disease often associated with chronic recurrent iridocyclitis.
    • Posterior spillover of inflammatory cells into the vitreous cavity can occur in severe cases.

    Observation:

    • Three eyes of two patients with ankylosing spondylitis presented with chronic iridocyclitis and posterior inflammatory cell spillover.
    • Significant vitreous opacification developed in all affected eyes due to persistent inflammation.

    Findings:

    • Pars plana vitrectomy and cataract extraction with subtotal vitrectomy led to improved and stabilized visual acuity in all three eyes.
    • Surgical intervention did not exacerbate ocular inflammation, and vitreous opacification did not recur post-vitrectomy.

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    Implications:

    • Vitrectomy is an effective treatment for vitreous opacification secondary to iridocyclitis in ankylosing spondylitis.
    • Chronic cystoid macular edema can limit visual recovery despite successful management of vitreous opacification.