[Season variations in lipolysis activity of adipocytes from fox, badger and hedgehog]

1. We have studied the seasonal variations of the lipolytic response to a beta agonist, isoproterenol, and to theophylline of the isolated adipocyte from fox, badger and hedgehog, related to the circannual variations of testes and thyroid activities. 2. With the fox, we find a coincidence, in spring, between the maximum lipolytic sensitivity of the adipocyte, the thyroid function and the return to sexual rest. 3. With the badger, in winter, the maximum reaction of the adipocyte is contemporary with testes activity and with thyroid rest. 4. With the hedgehog, we observe two maximums in the sensitivity of the adipocyte to the lipolytic agents, one in spring, which coincides with the maximal testes and thyroid activities, the other in autumn, before the deep hibernation state. 5. In conclusion, there is, with these wild mammals, a seasonal variation in the lipolytic reaction of adipocyte which coincides with that of energy needs.