Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Posterior urethral valves: theoretical considerations on embryological development.

D H Frohneberg, J W Thüroff, H Riedmiller

    European Urology
    |January 1, 1982
    PubMed
    Summary

    Posterior urethral valves cause severe urinary obstruction in children, with unclear origins. Types I and III valves may stem from persistent embryonic tissues, but Type II valve existence is debated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Robot-Assisted Transvesical Enucleation of Benign Prostatic Hyperplasia: Lessons from a Single Surgeon's Learning Curve.

    Urology practice·2023
    Same author

    Surgical treatment of large volume prostates: a matched pair analysis comparing the open, endoscopic (ThuVEP) and robotic approach.

    World journal of urology·2018
    Same author

    Long-term results of ProACT primary and repeat implantation for treatment of stress urinary incontinence in men.

    World journal of urology·2018
    Same author

    Aktuelle Urologie·2018
    Same author

    Survival outcomes in patients with large (≥7cm) clear cell renal cell carcinomas treated with nephron-sparing surgery versus radical nephrectomy: Results of a multicenter cohort with long-term follow-up.

    PloS one·2018
    Same author

    Mucin-Poor Mucinous Tubular and Spindle Cell Carcinoma of the Kidney Presented with Multiple Metastases Two Years after Nephrectomy: An Atypical Behaviour of a Rare, Indolent Tumour.

    Case reports in urology·2018

    Area of Science:

    • Pediatric Urology
    • Embryology
    • Congenital Malformations

    Background:

    • Posterior urethral valves are a primary cause of severe infravesical obstruction in children.
    • The precise etiology and embryological development of posterior urethral valves remain largely unknown.
    • Existing theories link Type I valves to Wolffian duct migration and Type III to the urogenital membrane.

    Purpose of the Study:

    • To explore the embryological origins of different types of posterior urethral valves.
    • To investigate the potential developmental pathways leading to urethral obstruction in children.

    Main Methods:

    • Review of embryological theories regarding urethral development.
    • Analysis of proposed mechanisms for Type I, II, and III posterior urethral valves.

    Related Experiment Videos

  • Examination of case data (65 cases) to assess the prevalence of different valve types.

    • Main Results:

    • Posterior urethral valves (PUVs) are a significant cause of pediatric infravesical obstruction.
    • Type I PUVs are hypothesized to arise from persistent connective tissue during Wolffian duct migration.
    • Type III PUVs are suggested to originate from residual urogenital membrane tissue; Type II valve existence is uncertain and was not observed in the study's cases.

    Conclusions:

    • The embryological basis for posterior urethral valves, particularly Types I and III, involves persistent embryonic tissues.
    • The existence and developmental origin of Type II posterior urethral valves require further investigation.
    • Understanding these embryological links is crucial for diagnosing and managing congenital urethral malformations.