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[Asymmetrical hypertrophic cardiomyopathy in neonates of diabetic mothers]
Archives Francaises De Pediatrie
|August 1, 1982
Insights
Diabetic mothers
Area of Science:
- Cardiology
- Neonatology
- Endocrinology
Context:
- Maternal diabetes can affect fetal cardiac development.
- Neonates of diabetic mothers are at increased risk for cardiovascular abnormalities.
Purpose:
- To investigate the prevalence and characteristics of hypertrophic cardiomyopathy in neonates born to diabetic mothers.
Summary:
- Echocardiography revealed hypertrophic cardiomyopathy in 6 out of 11 neonates of diabetic mothers.
- This condition, often benign and self-resolving, can sometimes present with obstructive symptoms.
Impact:
- Highlights the importance of cardiac screening in neonates of diabetic mothers.
- Suggests fetal hyperinsulinism as a potential cause for this cardiomyopathy.
Abstract:
In 11 neonates of diabetic mothers echocardiography was systematically performed and led to the discovery of 6 cases with hypertrophic cardiomyopathy. This abnormality, which may induce cardiorespiratory failure, is usually benign and consists of systolic murmur and transitory cardiomegaly; all these symptoms spontaneously regress within a few weeks. This cardiomyopathy may present with obstructive signs requiring treatment with beta adrenergic blocking agents; however, it is more often pure and needs no treatment. It may be observed after pregnancies that were not well supervised and might be induced by fetal hyperinsulinism.