Evaluation of the effect of p-chloroamphetamine on individual catecholaminergic nuclei in the rat brain

Short and long term effects of p-chloroamphetamine (PCA) on levels of catecholamines (CA) in discrete CA cell body and axon terminal areas were investigated. The levels were unaffected, except for a transient fall in dopamine in the arcuate nucleus. These results do not support the suggestion that PCA is neurotoxic to CA cells.