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[Sterile eosinophilic pustulosis (author's transl)]
Dermatologica
|January 1, 1978
Summary
Eosinophilic pustular folliculitis, also known as sterile eosinophilic pustulosis, presents with pustules and blood eosinophilia. This condition can lead to scarring alopecia and may respond to DADPS treatment.
Area of Science:
- Dermatology
- Pathology
Context:
- Eosinophilic pustular folliculitis (EPF), first described in Japan, is a rare skin condition.
- Recent reports indicate its occurrence beyond Japan, suggesting a broader geographical distribution.
Purpose:
- To report the first observed case of eosinophilic pustular folliculitis in the FRG.
- To propose the term "sterile eosinophilic pustulosis" to better describe the clinical presentation.
- To discuss differential diagnoses and potential treatment options.
Summary:
- The case involved a patient presenting with aggregated pustules rich in eosinophils and significant blood eosinophilia.
- The lesions initially appeared on the scalp, resulting in scarring alopecia.
- The authors suggest "sterile eosinophilic pustulosis" due to lesions extending beyond follicles and deep dermal eosinophilic infiltration, distinguishing it from conditions like Morbus Duhring.
Impact:
- Highlights the need for broader recognition of eosinophilic pustular folliculitis in clinical practice.
- Contributes to the understanding of the disease's clinical spectrum and nomenclature.
- Suggests Dapsone (DADPS) as a potential therapeutic agent for sterile eosinophilic pustulosis.