[Enhanced antitumor effect in the combined action of a magnetic field and hypothermia]

To substantiate some concepts of an oxygen-peroxide model of carcinogenesis, a number of experiments were conducted, and also the data were utilized previously obtained by the writers on the directed flow of water dissolved oxygen influenced by a permanent magnetic field. The observed suppressive action of the magnetic field on the growth of transplantable Pliss lymphosarcoma and PC-1 tumor may be accounted for the latter uncoupling oxygen in actively growing hyperoxic neoplastic cells from other participants of the direct free radical oxidation, spliting or minimizing in them closed cycles of reproduction of toxic products of lipids hyperoxidation. The enhanced effect of magnetic therapy under hypothermia is due to the well-known property of oxygen to change its magnetic susceptibility under the influence of temperature.