Control of luteal function and implantation in the mink by prolactin

Mink (Mustela vison) were treated during the period of embryonic diapause with prolactin or ergocryptine (CB-154). Prolactin advanced implantation time and hastened onset of luteal phase progesterone secretion. Duration of gestation in prolactin-treated adult mink was shorter than that of control mink. Ergocryptine had the opposite effects, prolonging gestation and inhibiting onset of luteal phase progesterone secretion. Prolactin is suggested to be the luteotrophin necessary for termination of embryonic diapause in mink.