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Abstract:
Penicillin is still the drug of first choice for the treatment of Syphilis and Gonorrhoea. The therapy of infections with Treponema pallidum requires long lasting stabile blood and tissue levels, Neisseria gonorrhoeae can be eradicated by high serum concentrations of short duration. Chancroid and Donovanosis respond well to tetracylines, macrolide antibiotics and aminoglycosides while the application of sulfonamides or tetracyclines is suitable for the control of Lymphogranuloma venereum. Metronidazole or nimorazole derivatives may cure Trichomoniasis. Infections with Mycoplasmas (Urea-plasma) or Chlamydiae can be treated by tetracyclines only. Genital candidosis usually disappears after topical use of miconazole- or econazole- or clotrimazole-ointments. Herpes genitalis cannot be influenced by pharmacotherapeutical means, relapsing forms may be suppressed by vaccination. Mollusca contagiosa should be removed by the surgical spoon and genital warts can be destroyed by electrocautherization or by topical application of podophyllin solution.