Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Brain elasticity changes with ventriculomegaly.

F H Sklar, J T Diehl, C W Beyer

    Journal of Neurosurgery
    |August 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Climate change projected effects on coastal foundation communities of the Greater Everglades using a 2060 scenario: need for a new management paradigm.

    Environmental management·2014
    Same author

    Tegaserod for the treatment of irritable bowel syndrome and chronic constipation.

    The Cochrane database of systematic reviews·2007
    Same author

    Tegaserod for the treatment of irritable bowel syndrome.

    The Cochrane database of systematic reviews·2004
    Same author

    Johann Friedrich August von Esmarch--a pioneer in the field of emergency and disaster medicine.

    Resuscitation·2001
    Same author

    Upper gastroduodenal ulceration in arthritis patients treated with celecoxib.

    The Annals of pharmacotherapy·2001
    Same author

    The role of preoperative radial artery ultrasound and digital plethysmography prior to coronary artery bypass grafting.

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2001
    Same journal

    Extent of resection as an independent predictor of survival for patients with glioblastoma as defined by the new WHO 2021 classification.

    Journal of neurosurgery·2026
    Same journal

    Surgical treatment of schwannomas around the tarsal tunnel: a case series of 40 patients and systematic review of the literature.

    Journal of neurosurgery·2026
    Same journal

    Direct targeting for focused ultrasound thalamotomy in the treatment of movement disorders.

    Journal of neurosurgery·2026
    Same journal

    Development and internal validation of the Meningioma Functional Outcome Risk and Counseling Estimator 6 score, a point-based prognostic tool for predicting 6-week functional independence after intracranial meningioma resection.

    Journal of neurosurgery·2026
    Same journal

    Connectional anatomy of the cerebellum: dentate nucleus and cerebellar peduncles from a surgical perspective.

    Journal of neurosurgery·2026
    Same journal

    Press releases in neurosurgery: is scientific accuracy compromised in public reporting of neurosurgery research?

    Journal of neurosurgery·2026
    See all related articles

    Brain elasticity, measured by pressure-volume relationships during cerebrospinal fluid infusions, shows a linear link with ventricular size. Hydrocephalic patients exhibit greater intracranial pulse amplitude, suggesting etiological importance in CSF disorders.

    Area of Science:

    • Neurosurgery
    • Neurology
    • Biomedical Engineering

    Background:

    • Cerebrospinal fluid (CSF) dynamics are crucial for brain health.
    • Understanding brain elasticity is key to diagnosing and managing CSF disorders.
    • Previous research has explored pressure-volume relationships but lacked precise measurement of CSF absorptive capacity.

    Purpose of the Study:

    • To determine the pressure-volume relationship of brain elasticity.
    • To measure net cerebrospinal fluid (CSF) absorptive capacity.
    • To investigate the link between ventricular size and brain elasticity in patients.

    Main Methods:

    • Servo-controlled variable-rate lumbar infusions were performed on 32 patients.
    • Brain elasticity and pressure-volume relationships were analyzed.

    Related Experiment Videos

  • Ventricular size was estimated using computerized tomography (CT) scans.

    • Main Results:

    • A linear relationship was observed between ventricular size and the elasticity slope (natural logarithm of pressure to volume).
    • Hydrocephalic patients demonstrated a greater intracranial pulse amplitude at equivalent pressures compared to normal individuals.
    • The findings suggest elasticity changes may be linked to ventriculomegaly.

    Conclusions:

    • The pressure-volume elasticity relationship appears to be linearly correlated with ventricular size.
    • Increased intracranial pulse amplitude in hydrocephalic patients is a significant finding.
    • The pressure-volume elasticity relationship may play an etiological role in cerebrospinal fluid system disorders.