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Butriptyline: improved gas-liquid chromatographic method using a nitrogen-phosphorus detector for its determination
Clinical Biochemistry
|August 1, 1980
Abstract:
We report a sensitive and specific method for the determination of butriptyline concentrations in serum by gas-liquid chromatography with a nitrogen phosphorus detector. The detection limit is 2 ng/ml, based on 3 ml of serum or plasma. The method has been validated in human volunteers receiving a single oral dose of 75 mg butriptyline hydrochloride.