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[Effects of intrapartum steroid prophylaxis on complement C3 and total complement activities (author's transl)]
One single high dose of dexamethasone (0.5 mg/kg body weight) was administered to a mother, before tests started into the effects of such approach upon the serum total complement (CH 50) and C-3 levels in the mother's umbilical cord blood. Neither CH 50 nor C-3 complement had declined with significance 48 hours from steroid administration. Significant reduction was observed only in cases in which six hours elapsed between steroid administration and childbirth.
One single high dose of dexamethasone (0.5 mg/kg body weight) was administered to a mother, before tests started into the effects of such approach upon the serum total complement (CH 50) and C-3 levels in the mother's umbilical cord blood. Neither CH 50 nor C-3 complement had declined with significance 48 hours from steroid administration. Significant reduction was observed only in cases in which six hours elapsed between steroid administration and childbirth.