[Phagocytic and lymphoid elements in tissue reactions during aseptic inflammation]

A foreign body was introduced into the rabbit abdominal cavity. Macrophages, polymorphonuclear leukocytes (PMNL), lymphocytes of the abdomino-cavitary exudate, blood, trachea were examined cytochemically, whilst the tissue being formed around the foreign body and lungs were subjected to histological study. It was shown that three levels of structural and functional reconstitution of macrophages, PMNL and lymphocytes accompanied the development of aseptic inflammation. The system level determines the likeness of alterations of macrophages, PMNL and lymphocytes of different sites. The regional and cellular levels are responsible for the difference between the cells of different sites and types. A relationship was disclosed between the system reconstitution and the local (capsule) and distant (lung) tissue inflammation. The alterative and exudative tissue processes depend on the damage to macrophages, PMNL and lymphocytes. Meanwhile the proliferative processes depend on the changes in the biosynthesis of these cells.