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Related Experiment Videos

Conjoined acardiac monsters.

J C Amatuzio, R J Gorlin

    Archives of Pathology & Laboratory Medicine
    |May 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    This study reports the first known case of conjoined acardiac monsters in a twin pregnancy, sharing vital arteries and a primitive heart. It also presents a classification and potential causes for this rare congenital anomaly.

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    Area of Science:

    • Perinatology
    • Developmental Biology
    • Medical Genetics

    Background:

    • Conjoined twins are a rare complication of monozygotic twinning.
    • Acardiac twinning, a specific form of conjoined twinning, involves a non-viable parasitic twin lacking a heart and lower body.
    • The exact etiology of acardiac twinning remains incompletely understood.

    Purpose of the Study:

    • To report the first documented case of conjoined acardiac monsters in a twin pregnancy.
    • To describe the unique vascular and cardiac anatomy of the acardiac twins.
    • To propose a classification and discuss potential developmental mechanisms for acardiac twinning.

    Main Methods:

    • Case report detailing a twin pregnancy with conjoined acardiac monsters.
    • Anatomical description of shared vascular structures and cardiac morphology.

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  • Review of existing literature for acardia classification and proposed etiologies.

    • Main Results:

    • The conjoined acardiac monsters shared a single abdominal-thoracic artery.
    • A primitive, single-chambered heart was observed in the conjoined twins.
    • The placenta was monoamniotic with two distinct umbilical cords.

    Conclusions:

    • This case represents a unique presentation of conjoined acardiac twinning.
    • Shared vascular supply and cardiac anomalies highlight the complex pathophysiology.
    • Further research into developmental mechanisms is warranted to understand and potentially prevent such anomalies.