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Limited subtotal thyroidectomy for Graves' disease.

R D Liechty, S G Silverberg, J Hernandez

    Archives of Surgery (Chicago, Ill. : 1960)
    |May 1, 1981
    PubMed
    Summary
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    Limited subtotal thyroidectomy effectively treats Graves' disease, maintaining thyroid function and minimizing complications. Most patients remained euthyroid long-term with low recurrence rates.

    Area of Science:

    • Endocrinology
    • Surgical Oncology
    • Thyroid Surgery

    Background:

    • Graves' disease is an autoimmune disorder causing hyperthyroidism.
    • Surgical management of Graves' disease aims to restore euthyroidism while minimizing risks.
    • The extent of thyroid resection impacts postoperative function and complication rates.

    Purpose of the Study:

    • To evaluate the efficacy and safety of limited subtotal thyroidectomy for Graves' disease.
    • To assess long-term thyroid function and recurrence rates following the procedure.
    • To determine the impact of remaining thyroid volume on postoperative outcomes.

    Main Methods:

    • A retrospective analysis of 43 patients with Graves' disease undergoing limited subtotal thyroidectomy.
    • Follow-up assessment of thyroid function, including euthyroid status and thyrotoxicosis recurrence.

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  • Histopathological examination for incidental thyroid cancers.

    • Main Results:

    • 87% of patients remained euthyroid at an average follow-up of 54 months.
    • Only 4.3% experienced recurrent thyrotoxicosis.
    • No deaths or permanent complications were reported; four patients had incidental papillary thyroid cancers.

    Conclusions:

    • Limited subtotal thyroidectomy is a safe and effective surgical option for Graves' disease.
    • Preserving thyroid tissue volume is crucial for maintaining postoperative thyroid function.
    • The procedure offers a favorable balance between efficacy, complication rates, and recurrence risk.