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Hypothyroidism after thyroidectomy for Graves' disease.

M B Farnell, J A van Heerden, W M McConahey

    American Journal of Surgery
    |November 1, 1981
    PubMed
    Summary
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    Subtotal thyroidectomy for Graves

    Area of Science:

    • Endocrinology
    • Surgical Oncology

    Background:

    • Graves' disease is an autoimmune disorder leading to hyperthyroidism.
    • Subtotal thyroidectomy was a common surgical treatment for Graves' disease.

    Purpose of the Study:

    • To evaluate the long-term outcomes of subtotal thyroidectomy for Graves' disease.
    • To assess the rates of hypothyroidism, hypocalcemia, and vocal cord dysfunction after surgery.

    Main Methods:

    • Retrospective review of 100 patients who underwent subtotal thyroidectomy for Graves' disease between 1970 and 1975.
    • Analysis of postoperative complications including hypothyroidism, hypocalcemia, and vocal cord function.

    Main Results:

    • 75% of patients developed hypothyroidism within an average of 4.6 months post-surgery.

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  • 1% experienced permanent hypocalcemia, and 3% had unilateral vocal cord dysfunction.
  • A low recurrence rate of thyrotoxicosis (1%) was achieved.

    • Conclusions:

    • Subtotal thyroidectomy for Graves' disease is associated with a high incidence of postoperative hypothyroidism.
    • The surgical approach led to a low recurrence of hyperthyroidism but significant morbidity.
    • Current practice at the institution favors less frequent use, restricted to younger patients.