Lymphosarcoma in an Eastern king snake and a rhinoceros viper

An antemortem diagnosis of lymphosarcoma was made in a captive Eastern king snake and a rhinoceros viper. The Eastern king snake died on the 1st day after biopsy of a liver nodule, and necropsy revealed multiple tumor nodules throughout all major organ systems. The rhinoceros viper died after chemotherapy with cytosine arabinoside. The major gross lesion was a large paracolonic coelomic tumor that extended into the adjacent musculature and subcutaneous tissue of the lateral abdominal wall. The immediate cause of death of the rhinoceros viper was believed to be severe renal tubular necrosis.