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Related Experiment Videos

Sequential histologic study of evolving lentigo maligna melanoma.

S F Cramer, C L Kiehn

Archives of Pathology & Laboratory Medicine

|March 1, 1982

Summary

This study suggests malignant melanoma may develop from new, aggressive lesions in adjacent skin, possibly influenced by neural factors and nerve growth factor, rather than evolving from existing lower-grade tumors.

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Area of Science:

Dermatology
Oncology
Pathology

Background:

Malignant melanoma traditionally viewed as evolving from atypical melanocyte proliferation.
Progression involves stages from junctional nests to invasive and metastatic neoplasm.