[Comparative evaluation of the effect of tuftsin and its analogs on immunogenesis]

The immunomodulator effect of tuftsin (Thr-Lys-Pro-Arg) and some analogs has been demonstrated on mice. All the peptides administered during the inductive phase of immunogenesis increased the content of antibody-producing cells in the spleen. Tuftsin and D-Arg-tuftsin appeared to be the most effective. The peptides did not affect the immune response under other application schemes.