Repetitive responses in squid giant axons and their premature annihilation by additional brief depolarizing currents
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Updated: Oct 19, 2026

Physiological Recordings of High and Low Output NMJs on the Crayfish Leg Extensor Muscle
Published on: November 17, 2010
Abstract:
The repetitive responses induced in squid giant axons by the application of sustained depolarizing currents under space clamp conditions are described. The relationships between membrane current, and a number of features of the repetitive response of the living axon are compared to computations made for the Hodgkin-Huxley equations. The comparison suggests that these equations adequately predict the form of the repetitive response, even so far as the ability of a brief additional depolarization to cause a premature end to the repetitive response.
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