Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypothesis Test for Test of Independence01:16

Hypothesis Test for Test of Independence

The test of independence is a chi-square-based test used to determine whether two variables or factors are independent or dependent. This hypothesis test is used to examine the independence of the variables. One can construct two qualitative survey questions or experiments based on the variables in a contingency table. The goal is to see if the two variables are unrelated (independent) or related (dependent). The null and alternative hypotheses for this test are:
H0: The two variables (factors)...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Production of Alcohol01:27

Production of Alcohol

Continuous fermentation is a key strategy in industrial ethanol production, particularly when efficiency, scalability, and high yields are essential. This approach allows for uninterrupted operation and optimized resource utilization. The primary feedstock, corn starch, undergoes enzymatic hydrolysis facilitated by α-amylase and glucoamylase. These enzymes break down the starch into fermentable sugars such as glucose, which are readily assimilated by fermentative microorganisms.Fermentation...
Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
Cirrhosis II: Pathophysiology01:24

Cirrhosis II: Pathophysiology

Cirrhosis is a progressive chronic liver injury caused by prolonged inflammation, excessive fibrotic remodeling, and impaired regeneration. Over time, repeated hepatic insults disrupt the liver’s architecture and function, leading to reduced blood flow, impaired bile drainage, and diminished metabolic capacity.Pathophysiology of cirrhosisCirrhosis arises from three main responses to chronic liver damage: inflammation, immune activation, and hepatocyte death. These processes lead to structural...
Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Introduction: intimate violence in communities of color.

Cultural diversity and mental health·1998
Same author

Comparing high school and college students' leisure interests and stress ratings.

Behaviour research and therapy·1993
Same author

The effects of resection of the proximal part of the fibula on stability of the knee and on gait.

The Journal of bone and joint surgery. American volume·1991
Same author

The association of pathologic and mammographic characteristics of primary human breast cancers with "slow" and "fast" growth rates and with axillary lymph node metastases.

Cancer·1984
Same author

Acute carcinoma of the breast.

Surgery, gynecology & obstetrics·1983
Same author

Psychological status among female candidates for surgical treatment of obesity.

International journal of obesity·1983

Related Experiment Video

Updated: Jul 9, 2026

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
07:31

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

Published on: January 7, 2019

A further look at the Institutionalized Chronic Alcoholic Scale.

R J Rhodes, A F Chang

    Journal of Clinical Psychology
    |July 1, 1978
    PubMed
    Summary

    A new MMPI scale, the Institutionalized Chronic Alcohol Scale (ICAS), effectively distinguishes alcoholics from neurotics. However, it is less accurate than existing scales and not recommended for differentiating alcoholics from other patient groups.

    Area of Science:

    • Psychological assessment
    • Clinical psychology
    • Addiction research

    Background:

    • The need for accurate diagnostic tools in identifying alcoholism.
    • Limitations of existing scales in differentiating alcoholics from other clinical populations.

    Purpose of the Study:

    • To evaluate the efficacy of a newly developed MMPI scale, the Institutionalized Chronic Alcohol Scale (ICAS).
    • To assess the ICAS's ability to differentiate between male alcoholics and neurotic patients.

    Main Methods:

    • Utilized a sample of 75 alcoholic and 50 neurotic male inpatients from Veterans Administration Hospitals.
    • Administered the ICAS and compared its diagnostic accuracy with established alcoholism scales (MacAndrew and Holmes).
    • Included data from 30 male heroin addicts to assess scale specificity.

    More Related Videos

    The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
    05:40

    The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

    Published on: April 28, 2022

    Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis
    08:45

    Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis

    Published on: November 8, 2024

    Related Experiment Videos

    Last Updated: Jul 9, 2026

    Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
    07:31

    Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice

    Published on: January 7, 2019

    The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
    05:40

    The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

    Published on: April 28, 2022

    Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis
    08:45

    Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis

    Published on: November 8, 2024

    Main Results:

    • The ICAS demonstrated a 78% accuracy in distinguishing alcoholics from neurotics.
    • Its effectiveness was found to be slightly lower than the MacAndrew (Amac) and Holmes (Am) scales.
    • Data suggested the ICAS is not suitable for differentiating alcoholics from non-neurotic patient groups, such as heroin addicts.

    Conclusions:

    • The ICAS shows promise in identifying alcoholics among neurotic patients but is not superior to existing measures.
    • Further research is needed to refine the ICAS and determine its appropriate clinical applications.
    • The scale's limitations necessitate caution when applying it to diverse patient populations beyond neurotics.