Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Minor nucleic acids in influenza virus.

E Harms, W Rohde, C Scholtissek

    The Journal of General Virology
    |September 1, 1978
    PubMed
    Summary

    Purified influenza virus contains minor amounts of RNA and DNA. For fowl plague virus, specific RNA sequences code for polymerase complex and matrix proteins.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Spinal muscular atrophy : Time for newborn screening?]

    Der Nervenarzt·2017
    Same author

    A fundamental concept for analytical psychology of childhood; paternus and materna.

    The Nervous child·2010
    Same author

    Equilibrium neurosis.

    Diseases of the nervous system·2010
    Same author

    Carl Gustav Jung; defender of Freud and the Jews; a chapter of European psychiatric history under the Nazi yoke.

    The Psychiatric quarterly·2010
    Same author

    Ego-inflation and ego-deflation.

    The Nervous child·2010
    Same author

    Alfred Adler in American psychotherapy.

    Individual psychology bulletin·2010

    Area of Science:

    • Virology
    • Molecular Biology
    • Genetics

    Background:

    • Influenza viruses are significant human and animal pathogens.
    • Understanding viral genetic material is crucial for developing antiviral strategies.
    • Previous research has characterized the major components of influenza virus RNA.

    Purpose of the Study:

    • To identify and characterize minor nucleic acid fractions in purified influenza virus.
    • To determine the origin and function of these nucleic acid sequences.
    • To investigate the specific gene sequences present in fowl plague virus (FPV) RNA.

    Main Methods:

    • Purification of influenza virus particles.
    • Analysis of nucleic acid content using molecular weight determination.
    • Identification of specific RNA sequences through gene mapping.

    Main Results:

    • A minor nucleic acid fraction (RNA and DNA) with a molecular weight of 1.4-1.5 x 10(6) was detected in purified influenza virus.
    • The identified RNA component is virus-specific.
    • In FPV, this RNA contains gene sequences 2 and 7, which encode proteins for the polymerase complex and the matrix protein, respectively.

    Conclusions:

    • Influenza virus preparations contain previously uncharacterized minor nucleic acid components.
    • These components, particularly the virus-specific RNA in FPV, play a role in viral replication and assembly.
    • Further investigation into these minor nucleic acid fractions may reveal novel targets for antiviral therapies.

    Related Experiment Videos