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[Effective employment of rubella-immunoglobulin (author's transl)]
Rubella and its complications during pregnancy must be taken seriously, as 12-15% of german females being able to deliver are encountered without protective immunity. Depending on gestational age rate of malformation goes up to 60%. To prevent embryopathy general vaccination of the population is considered to be most effective. Application of rubella-immunoglobulin to seronegative expectant mothers is an emergency measure. Necessary are high dosage and rapid injection after suspicion of ambient rubella. The need for high dosage and rapid injection is based on results of clinical investigations, that have been carried out during the recent years.
Rubella and its complications during pregnancy must be taken seriously, as 12-15% of german females being able to deliver are encountered without protective immunity. Depending on gestational age rate of malformation goes up to 60%. To prevent embryopathy general vaccination of the population is considered to be most effective. Application of rubella-immunoglobulin to seronegative expectant mothers is an emergency measure. Necessary are high dosage and rapid injection after suspicion of ambient rubella. The need for high dosage and rapid injection is based on results of clinical investigations, that have been carried out during the recent years.