Related Experiment Videos
[Therapy of bronchospasmic crisis of childhood with aminophylline]
La Pediatria Medica E Chirurgica : Medical and Surgical Pediatrics
|September 1, 1982
Insights
This study evaluated aminophylline with alcohol for childhood bronchospasm, finding it useful when theophylline blood levels guide individualized dosing to manage adverse reactions.
Area of Science:
- Pediatric Pulmonology
- Pharmacology
Context:
- Bronchospasm is a common respiratory condition in children.
- Aminophylline is a medication used to treat bronchospasm.
Purpose:
- To evaluate the therapeutic activity, tolerance, and adverse reactions of a new aminophylline product (1.56% alcohol) in childhood bronchospasm.
- To determine optimal dosing strategies for this new formulation.
Summary:
- The new aminophylline formulation demonstrated therapeutic utility in pediatric patients.
- Individualized dosing based on theophylline blood levels is crucial for efficacy and safety.
- Monitoring blood levels helps manage potential adverse reactions.
Impact:
- Provides evidence for the use of an alcohol-containing aminophylline formulation in pediatric care.
- Highlights the importance of therapeutic drug monitoring for aminophylline in children.
- Informs clinical practice regarding the safe and effective management of childhood bronchospasm.
Abstract:
We tested a new product containing aminophylline with 1,56% alcohol as therapy of bronchospasm in childhood to evaluate therapeutic activity, tolerance and adverse reactions. Authors confirm the usefulness of this product in childhood but dosage must be individualized with monitoring of theophylline blood levels.