Related Experiment Video

Updated: Aug 7, 2026

Isolation, Processing and Analysis of Murine Gingival Cells
09:47

Isolation, Processing and Analysis of Murine Gingival Cells

Published on: July 2, 2013

Gingival matrix collagen in chronic periodontitis

O Hammouda, M Seif, B Brinkley

    Journal of Dental Research
    |January 1, 1980
    PubMed

    More Related Videos

    Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model06:14

    Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model

    Published on: February 17, 2023

    Murine Model of Advanced Periodontitis Induced by Nylon Ligature in the Second Upper Molar07:14

    Murine Model of Advanced Periodontitis Induced by Nylon Ligature in the Second Upper Molar

    Published on: May 30, 2025

    Related Concept Videos

    The Extracellular Matrix01:42

    The Extracellular Matrix

    In order to maintain tissue organization, many animal cells are surrounded by structural molecules that make up the extracellular matrix (ECM). Together, the molecules in the ECM maintain the structural integrity of tissue as well as the remarkable specific properties of certain tissues.Composition of the Extracellular MatrixThe extracellular matrix (ECM) is commonly composed of ground substance, a gel-like fluid, fibrous components, and many structurally and functionally diverse molecules.
    The Extracellular Matrix01:29

    The Extracellular Matrix

    Overview
    In order to maintain tissue organization, many animal cells are surrounded by structural molecules that make up the extracellular matrix (ECM). Together, the molecules in the ECM maintain the structural integrity of tissue as well as the remarkable specific properties of certain tissues.
    Composition of the Extracellular Matrix
    The extracellular matrix (ECM) is commonly composed of ground substance, a gel-like fluid, fibrous components, and many structurally and functionally diverse...
    Matrix Proteoglycans and Glycoproteins01:21

    Matrix Proteoglycans and Glycoproteins

    Proteoglycans are extensively glycosylated proteins, commonly found in the extracellular matrix, interwoven with collagen fibers. Hyaline cartilage, the most common type of cartilage in the body, consists of short and dispersed collagen fibers associated with large amounts of proteoglycans. These proteoglycans have long negative charges that attract cations, which in turn attract water molecules. This influx of ions and water molecules swells up the proteoglycan like a water-soaked gel that can...
    Role of Matrix Metalloproteases in Degradation of ECM01:23

    Role of Matrix Metalloproteases in Degradation of ECM

    Matrix metalloproteases (MMPs) are enzymes involved in the hydrolysis of proteins and glycoproteins of the extracellular matrix. MMPs are essential for the migration and proliferation of cells through the dense matrix network, throughout embryonic development, and throughout morphogenesis. The first MMP activity discovered was a collagenase in a tadpole's tail undergoing metamorphosis. The active collagen deposition and modifications lead to the morphogenesis of tadpoles into the adult body.
    A...
    Phases of Wound Repair01:28

    Phases of Wound Repair

    Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
    Formation of Blood Clot
    In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
    Extracellular Matrix01:26

    Extracellular Matrix

    Unlike epithelial tissue, which is composed of cells closely packed with little or no extracellular space in between, connective tissue cells are dispersed in a matrix. This extracellular matrix (ECM) is composed of fibrous proteins like collagen, elastin, and fibronectin in a ground substance consisting of interstitial fluid, cell adhesion proteins, and proteoglycans. The proteoglycans form a gel-like material in the spaces between cells and provide hydration, buffering, binding, and force...