Clinical and laboratory studies on human sclera allografts

In the first section of this two-part report human peripheral blood leukocytes were tested for reactivity to extracts of sclera. Absence of scleral antigenicity is suggested by the results which showed that the leukocytes reacted similarly in sclera stimulated cultures and in the controls. The second part of the report discusses the clinical aspects of sclera allografts and provides guidelines for their clinical use. A case is presented where a sclera graft was in position for approximately a year. The tooth was removed with the attached graft and a histologic study made.