Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Low-dose radiation and leukemia.

A Linos, J E Gray, A L Orvis

    The New England Journal of Medicine
    |May 15, 1980
    PubMed
    Summary

    Low-level radiation exposure, under 300 rads to bone marrow, did not increase leukemia risk in a matched case-control study. This finding applies to radiation administered over long periods, typical in medical care.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Global advances and future directions in lung cancer care: expert consensus and strategic priorities.

    ESMO open·2026
    Same author

    Healthy diets positively associated with health-related quality of life in children and adolescents from low socioeconomic areas: Findings from the Greek Food Aid Program, DIATROFI.

    Nutrition (Burbank, Los Angeles County, Calif.)·2024
    Same author

    Gene-specific expression and calcium activation of Arabidopsis thaliana phospholipase C isoforms.

    The New phytologist·2021
    Same author

    Sacituzumab govitecan, a Trop-2-directed antibody-drug conjugate, for patients with epithelial cancer: final safety and efficacy results from the phase I/II IMMU-132-01 basket trial.

    Annals of oncology : official journal of the European Society for Medical Oncology·2021
    Same author

    Author Correction: Rice plants overexpressing OsEPF1 show reduced stomatal density and increased root cortical aerenchyma formation.

    Scientific reports·2019
    Same author

    Patient preferences of chemotherapy treatment options and tolerance of chemotherapy side effects in advanced stage lung cancer.

    BMC cancer·2019

    Area of Science:

    • Oncology
    • Radiology
    • Epidemiology

    Background:

    • Leukemia is a significant health concern.
    • Understanding radiation's role in cancer development is crucial.
    • Previous studies on radiation and leukemia have yielded varied results.

    Purpose of the Study:

    • To investigate the association between low-level radiation exposure and leukemia development.
    • To determine if diagnostic and low-level therapeutic radiation doses impact leukemia risk.

    Main Methods:

    • A matched case-control study design was employed.
    • 138 leukemia patients from Olmsted County, Minnesota (1955-1974) were matched with two controls each.
    • Lifelong radiation exposure histories (diagnostic and therapeutic) were ascertained for all participants.

    Main Results:

    • No statistically significant increase in leukemia risk was observed for bone marrow radiation doses between 0 and 300 rads (3 Gy).
    • This finding held true for radiation administered in small doses over extended periods, as is common in routine medical care.

    Conclusions:

    • Low-level radiation exposure, as typically encountered in medical diagnostics and treatments, does not appear to elevate the risk of developing leukemia.
    • The findings suggest that the benefits of necessary medical radiation procedures outweigh potential risks regarding leukemia development at these dose levels.

    Related Experiment Videos