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Related Experiment Videos

An automatic sigh feature for animal ventilators.

R D Gibson, D G Gisser, J C Newell

    Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
    |March 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

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    A new device reliably delivers automatic deep breaths to animals during laboratory ventilation. This cost-effective system uses a solenoid valve to provide controlled deep breaths at set intervals, improving respiratory support.

    Area of Science:

    • Veterinary Medicine
    • Physiology
    • Biomedical Engineering

    Background:

    • Mechanical ventilation in laboratory animals is crucial for research.
    • Ensuring adequate lung inflation and preventing atelectasis is a common challenge.
    • Automatic delivery of deep breaths (sighs) can improve ventilation efficacy.

    Purpose of the Study:

    • To describe a novel, low-cost device for automatically delivering deep breaths to ventilated animals.
    • To provide a reliable method for enhancing lung volume maintenance during mechanical ventilation.
    • To detail the mechanism and control of the deep breath delivery system.

    Main Methods:

    • A device was developed utilizing a solenoid valve in the expiratory tubing of a standard laboratory ventilator.

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  • The device enables the animal to inspire 2-4 consecutive tidal volumes without expiration to simulate a deep breath.
  • Integrated circuits control the interval between deep breaths, selectable from 1 to 10 minutes.

    • Main Results:

    • The described device reliably provides automatic deep breaths to ventilated animals.
    • The system allows for adjustable deep breath frequency (intervals of 1, 2, 4, 6, 8, or 10 minutes).
    • The total parts cost for constructing the device is approximately $90.

    Conclusions:

    • This device offers a practical and affordable solution for implementing deep breaths in animal mechanical ventilation.
    • The automatic nature and adjustable intervals enhance the utility of the system for various research protocols.
    • The low cost makes this technology accessible for widespread use in laboratory settings.