[Urological complications in patients with multiple sclerosis (author's transl)]

Area of Science:

• Neurology
• Urology
• Medical Science

Context:

• Multiple sclerosis (MS) is a chronic neurological disease affecting the central nervous system.
• Bladder dysfunction is a common and often debilitating symptom in MS patients.
• Urodynamic evaluation is crucial for diagnosing and managing lower urinary tract symptoms in MS.

Purpose:

• To evaluate the urodynamic findings in patients with multiple sclerosis.
• To identify the prevalence of specific bladder dysfunctions, including detrusor hyperreflexia and sphincter dyssynergia.
• To assess the effectiveness of available conservative therapies for MS-related bladder issues.

Summary:

• Urodynamic evaluation of 63 MS patients revealed high rates of bladder hyperreflexia (64%) and external sphincter spasticity (57%).
• Internal sphincter hypertrophy/sclerosis was noted in 27% of patients.
• Surgical interventions were performed on 16 patients, while conservative treatments like Lioresal and Dibenzyran showed promise for managing detrusor overactivity and bladder neck spasticity.

Impact:

• Provides critical data on the urodynamic profile of MS patients, aiding in diagnosis and treatment planning.
• Highlights the significant impact of MS on bladder function and sphincter control.
• Suggests effective conservative management strategies, potentially reducing the need for invasive procedures and improving patient outcomes.