Fluorographical findings in familial primary amyloidosis

A 50-year-old man, diagnosed as having familial primary amyloidosis due to his systemic symptoms, family history, and to histological examination of biopsy specimens, was examined by fluorescein angiography. The following results were obtained: (1) The sheathing retinal artery showed a defect of dye filling in one region, but not in the other region. Dye leakage from the sheathing artery was observed. (2) The configuration of macular vessels was rough, a microaneurysma-like change and the leakage of dye were also recognized in the capillaries of this region. (3) It was speculated that vitreous opacity originated from vascular lesions.