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Related Experiment Videos

Acute promonocytic leukemia with ocular involvement.

K F Tabbara, J H Beckstead

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |June 1, 1980
    PubMed
    Summary

    Bilateral eye redness in an infant was linked to acute promonocytic leukemia. This case highlights the need to investigate malignancy in children presenting with sterile hypopyon.

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    Area of Science:

    • Ophthalmology
    • Pediatric Oncology
    • Hematology

    Background:

    • Ocular inflammation in infants can present with varied etiologies.
    • Early detection of pediatric malignancies is crucial for improved outcomes.

    Observation:

    • A 3-month-old male infant presented with bilateral eye redness.
    • Anterior chamber tap revealed large, immature blast cells.

    Findings:

    • The infant was diagnosed with acute promonocytic leukemia, confirmed by bone marrow aspiration and autopsy.
    • Comprehensive clinical, histopathological, histochemical, and electron microscopic studies were performed.

    Implications:

    • This case underscores the critical importance of investigating malignancy in pediatric patients with sterile hypopyon.
    • Ophthalmologists and pediatricians should consider hematologic malignancies in the differential diagnosis of unexplained pediatric hypopyon.

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