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Hirsutism: pathogenesis and treatment.

Australian and New Zealand Journal of Medicine

|April 1, 1980

Summary

This summary is machine-generated.

Hirsutism, a condition of excess androgen production, can be effectively managed with long-term hormonal suppressive treatment. Antiandrogens and physical depilation offer further therapeutic options for controlling hirsutism.

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Area of Science:

Endocrinology
Reproductive Medicine
Dermatology

Background:

Hirsutism is often an endocrinopathy requiring a structured treatment strategy.
Excess androgen production is a key factor in hirsutism development.
Ovarian pathology is a common source of androgens, with adrenal cortex involvement also noted.

Purpose of the Study:

To outline a rational approach to the treatment of hirsutism.
To discuss the primary sources of androgen excess in hirsutism.
To review current and potential future therapies for hirsutism.

Main Methods:

Review of endocrinological and pathological findings in hirsutism.
Evaluation of long-term hormonal suppressive treatments.
Assessment of antiandrogens and physical depilation as therapeutic adjuncts.

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Main Results:

Long-term hormonal suppressive therapy effectively controls hirsutism in most patients.
Ovaries are frequently identified as the primary source of excess androgens.
The adrenal cortex contributes androgen precursors, though less commonly the primary source.

Conclusions:

A rational, endocrinopathy-based approach facilitates effective hirsutism treatment.
Hormonal suppression is the mainstay for controlling hirsutism.
Antiandrogens and physical methods are valuable complementary therapies.