Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulmonary resection for metastatic sarcoma.

J F Huth, E C Holmes, S E Vernon

    American Journal of Surgery
    |July 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Does human melanoma express carcinoembryonic antigen?

    Anticancer research·2000
    Same author

    Is adjuvant radiotherapy necessary after positive lymph node dissection in head and neck melanomas?

    Annals of surgical oncology·2000
    Same author

    Second-time surgery for stage IV sarcoma (a model of sequential metastases)

    Journal of the American College of Surgeons·2000
    Same author

    The Augsburg Consensus. Techniques of lymphatic mapping, sentinel lymphadenectomy, and completion lymphadenectomy in cutaneous malignancies.

    Cancer·2000
    Same author

    Lymphatic mapping and focused analysis of sentinel lymph nodes upstage gastrointestinal neoplasms.

    Archives of surgery (Chicago, Ill. : 1960)·2000
    Same author

    Judging the therapeutic value of lymph node dissections for melanoma.

    Journal of the American College of Surgeons·2000
    Same journal

    Innovative management of Anterior Cutaneous Nerve Entrapment Syndrome (ACNES): A meta-analysis and introduction of a new robotic approach with patient-based algorithm.

    American journal of surgery·2026
    Same journal

    Does the risk outweigh the benefit? Clot progression, recanalization & complications of anticoagulation therapy in acute pancreatitis with concomitant splanchnic vein thrombosis.

    American journal of surgery·2026
    Same journal

    High and low body mass index and 90-day postoperative outcomes in patients with Crohn's disease undergoing abdominal surgery.

    American journal of surgery·2026
    Same journal

    Women with firearm injuries: A multicenter mixed-methods study.

    American journal of surgery·2026
    Same journal

    SBAS presidential address: A surgeon-scientist's journey from haptic science to digital performance metrics.

    American journal of surgery·2026
    Same journal

    Using Dr. Google and AI to stay informed.

    American journal of surgery·2026
    See all related articles

    Surgical resection is key for lung metastases from sarcoma, even with multiple tumors. Tumor doubling time predicts chemotherapy response, guiding prognosis and improving outcomes with better adjuvant lung therapies.

    Area of Science:

    • Oncology
    • Surgical Oncology
    • Pulmonary Medicine

    Background:

    • Surgical resection is a critical component in managing lung metastases from sarcoma.
    • Multiple bilateral metastases do not preclude surgical intervention.

    Purpose of the Study:

    • To evaluate the role of surgical resection in lung metastases from sarcoma.
    • To assess the utility of tumor doubling time in predicting chemotherapy response.
    • To emphasize the importance of adjuvant therapy for pulmonary disease.

    Main Methods:

    • Analysis of tumor doubling time to assess growth rate and chemotherapy sensitivity.
    • Evaluation of preoperative chemotherapy as an in vivo test for tumor sensitivity.
    • Review of outcomes following thoracotomy for pulmonary metastases.

    Related Experiment Videos

    Main Results:

    • Tumor doubling time accurately determines growth rapidity and chemotherapy response.
    • Preoperative chemotherapy offers an in vivo measure of tumor sensitivity, correlating with prognosis.
    • Microscopic residual disease in the lungs is a primary cause of post-surgical failure.

    Conclusions:

    • Surgical resection is a viable option for lung metastases in sarcoma patients.
    • Adjuvant therapy targeting microscopic pulmonary disease is crucial for improving outcomes after thoracotomy.