[Tumor models in animals for the elaboration of oncologic problems]

Three groups of tumor systems in animals must be differentiated: 1) xenogeneic, 2) allogeneic, 3) syngeneic systems. While the tumor is not genetically identical with the tumor host in xenogeneic and allogeneic systems, syngeneic models are distinguished by a homogeneous genetic background of tumor and host organism. Xenogeneic, allogeneic, and syngeneic inbred animal models, on the one hand, and spontaneously tumor development in outbred animals on the other, were introduced with which oncologic questions can be handled.